ENDEMIC GOITRE: THE CAUSATIVE FACTOR.

The Problem of Endemic Goitre.

The first is the classical type prevalent in mountainous regions, such as the Alps and Himalayas, occurring as a colloid-poor diffuse parenchymatous goitre in childhood, and as an adeno-parentchymatouts, nodular goitre, with its degenerative forms in adults. The second is the difJuse colloid goitre prevalent in lowland regions, such as the plains of Central Europe, and in England. The geographi...

Endemic goitre in Guinea.

Pathophysiology of Himalayan endemic goitre.

The mountain slopes of the Himalayas, Alps, Pyrenees, and Andes have been the world’s most notorious foci of endemic goiter (1). The northern frontiers of India extending from Kashmir in the west to Assam in the east form an extensive Himalayan goiter belt (2). Forty million persons are believed to be exposed to the risk ofgoiter in this belt and approximately nine million are afflicted with it...

Endemic Goitre in Greece: Family Studies.

The evidence implicating iodine deficiency in the aetiology of endemic goitre is overwhelming, and a deficiency of iodine in the diet has been accepted as the main cause of this condition (Kelly and Snedden, I960; Greer, I962; Wayne, Koutras, and Alexander, I964). Considerations of the quantitative aspects of iodine metabolism leave little doubt that in the presence of a sufficiently severe and...

The prevalence of endemic goitre among Penans of the Baram.

Two hundred and thirty three Penan households from the Silat area, Ulu Baram and the Tutoh of the Fourth Division, Sarawak, were studied with regards to the prevalence of endemic goitre and the consumption of iodised salt. Of the 343 Penan women aged 15 years and above who were examined, 60.6% had goitres. The serious nature of this, in the case of the Penans, is indicated by the fact that 39.3...